Cellular Bioenergetics Is Impaired In Patients With Chronic Fatigue Syndrome




From ME Research UK.



Cara Tomas C, Brown A, Strassheim V, Elson J, Newton J, Manning P


Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK


Chronic fatigue syndrome (CFS) is a highly debilitating disease of unknown aetiology. Abnormalities in bioenergetic function have been cited as one possible cause for CFS. Preliminary studies were performed to investigate cellular bioenergetic abnormalities in CFS patients. A series of assays were conducted using peripheral blood mononuclear cells (PBMCs) from CFS patients and healthy controls. These experiments investigated cellular patterns in oxidative phosphorylation (OXPHOS) and glycolysis. Results showed consistently lower measures of OXPHOS parameters in PBMCs taken from CFS patients compared with healthy controls.


To read the rest of this article, click on the link below:


Link to ME Research article

Leave a Reply

The York ME Community © 2015
Powered by Live Score & Live Score App