From The British Medical Journal.
Chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) can be distinguished from medical and psychiatric conditions in the differential diagnosis of fatigue by the presence of debilitating fatigue for more than 6 months; combinations of cognitive dysfunction, total body pain, and unrefreshing sleep that does not restore normal function; and postexertional malaise, where exertion or other stressors leads to exacerbation of these symptoms with onset immediately or delayed by several hours or overnight.
The World Health Organization classifies CFS/ME as a neurologic illness.
There are no objective diagnostic tests, verified biomarkers, curative medications, or treatments for CFS/ME. The primary goals of treatment are to manage symptoms and improve functional capacity. Initial treatment should be individualized based on the patient’s most severe complaints.
The chronic but fluctuating disabilities require substantial lifestyle changes to carefully plan each day’s activities, conserve energy resources for the most important tasks, schedule rest periods to avoid individuals overtaxing themselves, and to improve the quality of sleep.
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