Cortene – A New Drug For Chronic Fatigue Syndrome (ME/CFS) Pt III: The Clinical Trial



By Cort Johnson in Health Rising.


An Exploratory Drug Trial For ME/CFS

In the next month or so, Cortene, a small drug development company, will do a very unusual thing – trial a new drug in chronic fatigue syndrome (ME/CFS). The first two parts of the series on this new drug covered how ME/CFS came to the attention of Cortene, why Cortene believes ME/CFS is a possible match for its drug, and introduced Cortene’s novel hypothesis regarding ME/CFS.


Treatment Approach


The novel hypothesis proposes that a receptor called CRF2, which triggers neurons to release serotonin, has become unusually prevalent in parts of ME/CFS patients’ brains. Cortene believes that the elevated release of serotonin – in response to even small levels of stress – in turn causes ME/CFS.

In part three, we look at why Cortene thinks its CT38 drug may be able to reduce CRF2 levels, the possible side-effects of the drug, what past studies have told us about the drug, where Cortene is in the process of getting FDA approval for the trial, and the basic makeup of the trial.


To read the rest of this story, click on the link below:


Link to ME story

Leave a Reply

The York ME Community © 2015
Powered by Live Score & Live Score App