From The Microbe Discovery Project.
Our Microbe Discovery Project team had some time unplugged through the holiday period but while we were away momentum was building in the ME/CFS research world!
Straight off the bat there was some big news from Norway just before Christmas! Drs. Fluge and Mella et all AKA the Norwegian team, published a paper titled ‘Metabolic profiling indicates impaired pyruvate dehydrogenase function in myalgic encephalopathy/chronic fatigue syndrome’ in the Journal of Clinical Investigation Insight. This work in essence points to a possible PDH ( pyruvate dehydrogenase) block in people with ME/CFS. This is a key metabolic enzyme in the TCA (tricarboxylic acid cycle). Yes, that is an impairment in a very important part of energy metabolism within cells.
Dr Fluge has stated himself there is a long way to go but this is an incredibly interesting paper and we really encourage people to read the write ups. There was also coverage in Medscape by Miriam E. Tucker and ME/CFS was a top clinical trending search topic on Medscape for at least one week in January.
The Norwegian government is ahead of the pack, seeming to be listening and acknowledging the lack of research funding, education, social support and care needs for patients and families. This goes all the way to the top, check out a google translate of the Prime Minister of Norway Erna Solbergs recent blog about ME/CFS.
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