ME Research

The Big Fishing Expedition: Report From The NIH Intramural Study On ME/CFS


    By Cort Johnson in Simmaron Research.   The NIH’s Intramural Study on ME/CFS now underway is almost certainly the most comprehensive chronic fatigue syndrome (ME/CFS) study ever done. In fact, it may be one of the more multi-faceted studies done in any disease. It’s breadth is astonishing. Besides the blood, urine, fecal matter […]

Even “Minor” Infections Can Cause Chronic Fatigue Syndrome (ME/CFS)


By Cort Johnson in Simmaron Research.   Giardia hasn’t historically ranked high as a potential cause of chronic fatigue syndrome (ME/CFS). Some anecdotal reports suggest that a Giardia outbreak may have occurred prior to the Incline Village ME/CFS outbreak in the 1980’s. More recently, Corinne Blandino’s severe, decades long case of ME/CFS – which originated with […]

ME/Chronic Fatigue Syndrome

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  From The Quadram Institute.   A coordinated, collaborative approach is vital to understanding the origins of this complex, debilitating condition.   Myalgic Encephalomyelitis (ME), also known as Chronic Fatigue Syndrome (CFS), is a severely debilitating condition that is thought to affect up to 250,000 people in the UK. Symptoms include widespread pain, extreme tiredness […]

On Your Marks GETSET: Don’t Go – Major Graded Exercise ME/CFS Trial Underwhelms (Again)


    By Cort Johnson in Health Rising.   The Lancet — one of the most highly regarded journals in the world — is back on the chronic fatigue syndrome (ME/CFS) community’s front page. That’s probably enough to either elicit curses from ME/CFS patients or to produce a strong desire to hide under one’s bed. […]

Prevalence Of And Risk Factors For Severe Cognitive And Sleep Symptoms In ME/CFS And MS

Biomed Central

  From Biomed Central.  Authors as listed.   Abstract   Background There are considerable phenotypic and neuroimmune overlaps between myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and multiple sclerosis (MS). While the precise aetiologies of both MS and ME/CFS are unclear, evidence suggests that deterioration in cognitive function is widely prevalent in patients with either condition. Little […]

Viruses And CFS: Statements By Ron Davis And Bob Naviaux

Medicine Foundation

    From Open Medicine Foundation.   Ron Davis: There is a great deal of evidence that a variety of viruses can initiate ME/CFS, but it is less clear that a virus is involved in sustaining the disease. However, some patients may have a continuous problem with viruses, especially those viruses we always carry like […]

ME/CFS: A New Explanation – And Cure ?

Dr Eriksen

      From   In a recent paper, Dr. Willy Eriksen proposes a complete explanation for the development, diversity, and persistence of myalgic encephalomyelitis, aka chronic fatigue syndrome (ME/CFS). He also suggests a possible cure. Seeing that this potentially groundbreaking research was attracting little attention, I contacted Dr. Eriksen and interviewed him via […]

Could We Finally Have A Definitive Biomarker For ME/CFS ?


  From ME Research UK.   It’s a recurring theme, but the diagnosis of ME/CFS is severely hampered by the lack of a test that can distinguish people with the illness from those without. This is a challenge in many diseases, but particularly in ME/CFS which affects so many different systems of the body. ME/CFS […]

University of Toronto Study Offers Hope To Sufferers Of Chronic Fatigue Syndrome

University of Toronto

    From University of Toronto News.   A new U of T study may lead to help for sufferers of chronic fatigue syndrome (CFS) who face debilitating fatigue that can’t be cured by rest. The study, which looks at epigenetic changes in people with CFS, is the first to identify differences in sensitivity to a hormone found in the […]

ME/CFS Research Community Surprises: Submits Ten Research Center Applications to NIH

Cort Johnson

  By Cort Johnson in Health Rising.   The NIH Research Center applications are in. The NIH is surely looking closely at how the chronic fatigue syndrome (ME/CFS) research community responds. After all, they haven’t responded very well over time. A Freedom of Information Act (FOIA) request indicated that the NIH receives few – really […]

Vitamin And Mineral Status In Chronic Fatigue Syndrome And Fibromyalgia Syndrome: A Systematic Review And Meta-Analysis


      By Monica L. Joustra ,Isidor Minovic, Karin A. M. Janssens, Stephan J. L. Bakker, Judith G. M. Rosmalen Published: April 28, 2017   Abstract Background Many chronic fatigue syndrome (CFS) and fibromyalgia syndrome (FMS) patients (35–68%) use nutritional supplements, while it is unclear whether deficiencies in vitamins and minerals contribute to symptoms in these […]

NVCBR Researchers Close In On A Diagnostic Test For ME/CFS Patients


      From Nevada Center for Biomedical Research.   Physicians lack effective tools to aid in the diagnosis and treatment of those who are impacted by ME/CFS, a complex and often disabling disease.  That could change now that scientists at Nevada Center for Biomedical Research (NVCBR) have taken the first step in developing a […]

Human Heart, Cosmic Heart – ME/CFS/FM Heart ? A Review.


    By Remy in Health Matters.   A Review of “Human Heart, Cosmic Heart” by Dr. Thomas Cowan The heart is rarely front and center currently when it comes to discussing the system failures and dysregulation in ME/CFS. Despite the focus some doctors (specialists such as the late Dr. Lerner and Dr. Cheney) have […]

Ian Lipkin’s CII Team Shows Gut Bacteria In ME/CFS May Influence Disease Severity


  From The Microbe Discovery Project.   Anticipated work from the CII teams’ early investigative research into ME/CFS is starting to be published. The new study in the journal Microbiome from Drs Ian Lipkin and Mady Horning at Columbia University Center for Infection and Immunity (CII) finds abnormal levels of certain types of bacteria in the gut […]

The Stanford Paradox: Elevated Energy Production Found In Chronic Fatigue Syndrome (ME/CFS)

Blood Test

    By Cort Johnson in Health Rising.   Producing energy is a big problem in Chronic Fatigue Syndrome (ME/CFS). In fact it’s probably the problem in ME/CFS, which is why the findings of mitochondrial dysfunction and lowered ATP production have made sense. When the metabolomics studies suggested that chronic fatigue syndrome (ME/CFS) was a […]

Inflammation Test Could Be Tailor-Made For Chronic Fatigue Syndrome: Are The Mitochondria To Blame ?

Blood Test

      By Cort Johnson in Simmaron Research.   Inflammation is a big deal in the medical world.  Even mild inflammation, if it’s consistently present, is known to increase one’s risk of getting cardiovascular diseases, diabetes, Alzheimer’s and many others. Standard tests for inflammation such as C-reactive protein or cholesterol, however, are often unrevealing. For […]

Chronic Fatigue Syndrome And The Immune System: Where Are We Now ?

Pub Med

    By Mensah FKF, Bansal AS, Ford B, Cambridge G. in Pub Med.   Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is characterised by multiple symptoms including fatigue, headaches and cognitive impairment, which have a significantly adverse effect on the normal functioning and well-being of the individual. These symptoms are often triggered or worsened following physical or […]

GABA & Glutamate In Fibromyalgia & Chronic Fatigue Syndrome

Brain anatomy  - cross section

  By Adrienne Dellwo in Very Well. GABA and glutamate are neurotransmitters—chemical messengers in your brain. One is calming, one is stimulating, and they’re supposed to stay in balance with each other. So what happens if this balance is thrown off? Some research suggests an imbalance of these two substances may play a role in fibromyalgia […]

An Immunosignature Assay For Rituximab Therapy ?


    From ME Research UK.   Principal Investigator Prof. David Patrick Institution School of Population and Public Health, University of British Columbia, Vancouver, British Columbia, USA In many cases, the drugs used to treat various diseases are effective in only a proportion of patients. It can therefore be valuable to identify these individuals, so […]

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