ME Research

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients Exhibit Altered T Cell Metabolism And Cytokine Associations

Stem Cells

By Alexandra H. Mandarano, Jessica Maya, […], and Maureen R. Hanson in The Journal Of Clinical Investigation.   Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex disease with no known cause or mechanism. There is an increasing appreciation for the role of immune and metabolic dysfunction in the disease. ME/CFS has historically presented in outbreaks, […]

The Evidence Base For Physiotherapy In Myalgic Encephalomyelitis/Chronic Fatigue Syndrome When Considering Post-Exertional Malaise: A Systematic Review And Narrative Synthesis

Research

  By Marjon E. A. Wormgoor and Sanne C. Rodenburg in the Journal of Translational Medicine. Abstract Background Due to the inconsistent use of diagnostic criteria in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), it is unsure whether physiotherapeutic management regarded effective in ME/CFS is appropriate for patients diagnosed with criteria that consider post-exertional malaise (PEM) as a hallmark feature. […]

A Geneticist’s Quest To Understand His Son’s Mysterious Disease

Ron Davis

By Tracie White in The Scientist. Ronald Davis of Stanford University changed his focus to research on ME/CFS, the disease formerly known as chronic fatigue syndrome, in a bid to help his son and others like him.   About 10 years ago, Stanford University genomicist Ronald W. Davis began a new investigation into a mysterious […]

When Dr. Peter Rowe Speaks – We Should Listen: Dr. Rowe On ME/CFS At The Dysautonomia International Zoom Conference

Cort Johnson

  By Cort Johnson in Health Rising. A riff on Dr. Peter Rowe’s presentation at the 2020 Dysautonomia International Conference (note that I expand on many of Rowe’s points; i.e. not all the words are his.) Lauren Stiles, the founder of Dysautonomia International, has long believed that the chronic fatigue syndrome (ME/CFS) and dysautonomia fields […]

Ivabradine – Could A “Wonder Drug” For POTS Work In ME/CFS ?

johnson_cort

By Cort Johnson in Health Rising.   Ivabradine appears to work quite well in POTS  – but should we stop there? Ivabradine was approved for use in the European Union in 2005, but it’s pretty new to the scene in the U.S. It was FDA approved in only 2015. That means it doesn’t have much […]

An Early Christmas Present For Physios For ME

Research

From Physios For ME.   In May 2020 we were thrilled to announce that we had obtained funding from the ME Association Ramsey Research Fund for a study; “Feasibility of investigating oxygen consumption (VO2), heart rate, blood pressure, lactic acid levels and activity levels of people with Myalgic Encephalomyelitis during normal daily activities.” You can […]

Mitochondrial Enhancers For Chronic Fatigue Syndrome (ME/CFS) And Fibromyalgia Pt. I: D-Ribose, CoQ10 And PQQ

Mitochondrial

  By Cort Johnson in Health Rising. Is more energy the cure-all for chronic fatigue syndrome (ME/CFS) and fibromyalgia? Dr. Lerner observed years ago that symptoms in ME/CFS/FM tend to go up when energy levels go down and decline when energy levels go up. Even at rest, our muscles are affected by low energy levels. […]

Science Behind DecodeME Uncovers Potential Covid-19 Treatments

DNA-Double-Helix-made-of-people-DecodeME

  From DecodeME.   DecodeME’s Dr Veronique Vitart, Dr Shona Kerr and Professor Chris Ponting are among a group of researchers who have just published a study in the top science journal Nature on the role that genetics plays in severe Covid-19. Using the same technique that will power DecodeME, they found that people with particular DNA […]

Researchers Claim Proof Chronic Fatigue Syndrome Is A Bodily Disease – Expert Reaction

2-mitochondria

  From Science Media Centre. Researchers claim they have “unequivocally proved” that Chronic Fatigue Syndrome is not a psychosomatic disease. One of their studies finds mitochondria – known as the “powerhouse of the cell” – are dysfunctional in patients with the syndrome. A second study finds epigenetic similarities among sufferers. The SMC asked experts to comment on the research.  Associate […]

New Test For Chronic Fatigue Syndrome Could Help COVID-19 Patients

Blood Test

  By Erica Gerald Mason in Very Well Health.    Researchers have developed a new test to diagnose myalgic encephalomyelitis (ME), also known as chronic fatigue syndrome (CFS). The test stands out as the first successful molecular diagnostic tool for ME, a development that has been long anticipated by many healthcare providers and patients. This new tool […]

Blood MicroRNA Patterns Linked To Chronic Fatigue Syndrome

Blood Test

By Katarina Zimmer in The Scientist.   A finding of distinct patterns of gene-regulating RNA snippets in the blood of ME/CFS patients in response to a stress test could pave the way for a diagnostic tool for the condition and help untangle its underlying mechanisms. Formerly known as chronic fatigue syndrome, myalgic encephalomyelitis/chronic fatigue syndrome […]

Montreal Researchers Make Chronic Fatigue Syndrome Discovery

Blood Test

  By Jean-Benoit Legault  The Canadian Press. A discovery by Montreal researchers is expected to improve the diagnosis and treatment of patients with myalgic encephalomyelitis (ME), better known as chronic fatigue syndrome. In most instances, ME is currently diagnosed by elimination, as doctors put aside other possible causes of the patient’s symptoms. But researchers from the University […]

Illness-Related Fatigue: More Than Just Feeling Tired

Fatigue

  By Jennifer Crystal, MFA in Harvard Health Publishing.   A common refrain during the COVID-19 pandemic is, “I’m so tired.” After months of adjusted living and anxiety, people are understandably weary. Parents who haven’t had a break from their kids are worn out. Those trying to juggle working from home with homeschooling are stretched […]

A Never-Ending Immune Battle In ME/CFS ? The Regulatory T-cell / Herpesvirus Hypothesis

Blood Cells

By Cort Johnson in Simmaron Research. The failed Rituximab trial might seem like the death knell for autoimmunity in chronic fatigue syndrome (ME/CFS) but it’s not – not by a long shot. While the B-cells that Rituximab targeted are at the heart of much autoimmunity, T-cells can also cause autoimmune diseases. They also play a […]

Starving for Energy ? And The Immune Hole That Produced ME/CFS ?- The IACFS/ME Conference Reports Pt. II

Nervous System

By Cort Johnson in Health Rising.   The Immune Hole That Produced ME/CFS? (and who knows – maybe long-hauling as well) Somehow Lenny Jason got a hold of some recovery data from the 1918 flu! The data suggested that 20% of those affected may not have fully recovered, and fatigue was one of the most […]

Open Medicine Foundation Australia

Emerge

From Emerge Australia.   Established in October 2020, Open Medicine Foundation Australia (OMF Australia) is an Australian foundation set up to support biomedical research through the establishment of a new ME/CFS collaborative research centre in Australia. OMF Australia was founded by Emerge Australia in partnership with the Open Medicine Foundation, meaning that Australia is now […]

A Fatigue Nucleus In Multiple Sclerosis… And ME/CFS And Fibromyalgia ?

Brain anatomy  - cross section

By Cort Johnson in Health Rising. Fatigue has been a mystery to the research world. Take multiple sclerosis (MS) – one of the most fatiguing diseases known. Fatigue is often one of the first symptoms that shows up in MS and it’s often the most troubling symptom MS patients experience, yet the fatigue in MS isn’t […]

NHMRC Grant Boosts ME/CFS Research

Funding

  By Deborah Marshall in Griffith News. The National Centre for Neuroimmunology and Emerging Diseases (NCNED) has been awarded $1.46 million in National Health and Medical Research Council funding for research into myalgic encephalomyelitis /chronic fatigue syndrome (ME/CFS). Part of Griffith University’s Menzies Health Institute Queensland , the centre’s researchers will investigate potential diagnostic tests as well as suitable […]

Health And Wellbeing Survey 2019

Emerge

    From Emerge Australia.   Emerge Australia conducted a second Health and Wellbeing Survey of people living with myalgic encephalomyelitis/ chronic fatigue syndrome (ME/CFS) in 2019. An impressive 1,055 participants from around Australia answered 60 questions covering demographics, caring responsibilities, ME/CFS onset and symptom experience, access to healthcare and other services, and the effect […]

Understanding The Causes Of Chronic Fatigue Syndrome​ Through The Vagus Nerve

Vagus Nerve

  From Parasym.   Chronic Fatigue Syndrome: examining the impact of infections. Chronic Fatigue Syndrome/Myalgic Encephalomyelitis, or CFS, is a long-term illness that is characterised by extreme tiredness in addition to a host of other discomforts. Researchers have struggled to find an identifiable origin to this debilitating disease and as a result, it has proven […]

Is Ron Davis’s ME/CFS Collaborative Research Center At Stanford Poised For A Breakthrough ?

Ron Davis

    By Cort Johnson in Health Rising.   Ron Davis’s Stanford ME/CFS Collaborative Research Center is itching to get back to full-time lab work. It’s not that Davis and his group haven’t been working. Janet Dafoe described constant Zoom calls with ME/CFS researchers, a bevy of grant applications have been completed, put some researchers – with […]

Researchers Explore Clinical And Biological Aspects Of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

Research Study

  Reviewed by Emily Henderson, B.Sc in News Medical Life Sciences.   One of the major symptoms of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is post-exertional malaise (PEM), the worsening of symptoms after physical or mental activities. Using their own words and experiences, people with ME/CFS described how debilitating PEM can be in a study in Frontiers in […]

Covid 19 Coronavirus: Kiwi Expert On Covid Survivors Affected By ME

Research

  By: John Gibb in the Otago Daily Times.   In a cruel twist, many Covid-19 survivors could be affected by a once-obscure chronic fatigue condition, initially termed the Tapanui flu, and whose existence was once ridiculed and denied. Emeritus Prof Warren Tate, 73, of the University of Otago biochemistry department, officially retired recently but is continuing […]

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