Mitochondria and ME

Bioenergetic And Proteomic Profiling Of Immune Cells In Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients: An Exploratory Study

From MDPI. Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a heterogeneous, debilitating, and complex disease. Along with disabling fatigue, ME/CFS presents an array of other core symptoms, including autonomic nervous system (ANS) dysfunction, sustained inflammation, altered energy metabolism, and mitochondrial dysfunction. Here, we evaluated patients’ symptomatology and the mitochondrial metabolic parameters in peripheral blood mononuclear […]

Mitochondrial Enhancers For Chronic Fatigue Syndrome (ME/CFS) And Fibromyalgia Pt. I: D-Ribose, CoQ10 And PQQ

  By Cort Johnson in Health Rising. Is more energy the cure-all for chronic fatigue syndrome (ME/CFS) and fibromyalgia? Dr. Lerner observed years ago that symptoms in ME/CFS/FM tend to go up when energy levels go down and decline when energy levels go up. Even at rest, our muscles are affected by low energy levels. […]

Researchers Claim Proof Chronic Fatigue Syndrome Is A Bodily Disease – Expert Reaction

  From Science Media Centre. Researchers claim they have “unequivocally proved” that Chronic Fatigue Syndrome is not a psychosomatic disease. One of their studies finds mitochondria – known as the “powerhouse of the cell” – are dysfunctional in patients with the syndrome. A second study finds epigenetic similarities among sufferers. The SMC asked experts to comment on the research.  Associate […]

Broken Mitochondria Use ‘Eat Me’ Proteins To Summon Their Executioners

    From Eureka Alert. When mitochondria become damaged, they avoid causing further problems by signaling cellular proteins to degrade them. In a paper publishing April 11, 2019, in the journal Developmental Cell, scientists in Norway report that they have discovered how the cells trigger this process, which is called mitophagy. In cells with broken mitochondria, […]

Mitochondrial Complex Activity

  From ME Research UK. Cara Tomas and colleagues from Newcastle University have recently published a report on mitochondrial function in ME/CFS, and this study is related to research on muscle fatigue they are currently pursuing with support from ME Research UK. The mitochondria are considered the power plants of the body, generating the energy needed to […]

What About M.E.? Living With A Little Known And Widely Misunderstood Neurological Disease

    By Lori, in Rare Disease Day.   What About M.E.? Living with a Little Known and Widely Misunderstood Neurological Disease Myalgic Encephalomyelitis Chronic Fatigue Syndrome, or ME CFS for short, is the disabling disease that I’ve been diagnosed with and that has changed my life forever. First, some words about the disease itself. […]

Thiamine And Riboflavin For Chronic Fatigue

  By Chandler Marrs, PhD in Hormones Matter. From its title, Mitochondrial Myopathy in Follow-up of a Patient With Chronic Fatigue Syndrome, I doubt anyone would ascertain the importance of this case study, but a quick read of even just the abstract tells an entirely different story. A deeper dive into the full article reveals just how […]

Study Identifies Constellation Of Metabolites Linked To ME/CFS

  From News Medical Life Sciences.   A study led by researchers at the Center for Infection and Immunity (CII) at Columbia University’s Mailman School of Public Health has identified a constellation of metabolites related to myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Combining this data with data from an earlier microbiome study, the researchers now report […]

Cellular Energy Production Takes Big Hit In Chronic Fatigue Syndrome (ME/CFS) Study

  By Cort Johnson in Health Rising.   The two-day exercise study results suggest that the ability to produce energy after exercise in chronic fatigue syndrome (ME/CFS) is blunted, and the search is on to identify blockages in cellular energy that could explain that.  Lead by Cara Tomas, Julia Newton and company have stepped into […]

What I Learned At Stanford

  by TheSoberCannibal in Reddit.com.   I’ve been a patient at Stanford for a few years now but I just had a really good appointment with Dr Bonilla there where I learned some new things I wanted to share. I’m going to keep this short, bulleted, and as brainfog friendly as possible. I’ll make the first sentences […]

6 Nutrients That Improve The Well-Being Of Mitochondria, The Cell’s Power Plant

By Todd Runestad in New Hope. Each cell contains 1,500 mitochondria—organelle that are basically the cell’s power plant. In fact, some 60 percent of the cell’s volume is mitochondria. They have their own DNA and are passed along from mother to child. Because mitochondria accumulate in organs and tissues with a high need for energy, they are […]

Researchers Review Melatonin’s Therapeutic Potential For Mitochondrial Dysfunction-Related Diseases

    By Alice Meloa in Mitochondria Disease News. Researchers from the Shahrekord University of Medical Sciences, in Iran presented the most recent findings of the clinical effects of the hormone melatonin on the development of diseases related to mitochondrial dysfunction, such as diabetes, cancer, gastrointestinal diseases, and conditions related to brain function. The review […]

Mitochondrial Dysfunction, Post-Exertional Malaise And ME/CFS

    From The Massachusetts CFIDS/ME & FM Association.   The role of mitochondria in cellular function Except for red blood cells 1, every cell of the human body contains mitochondria—which are cellular bodies that manufacture the energy needed by the cell in order to function. The energy is essentially created by the conversion of ATP (adenosine […]

The Care And Feeding Of Your Mitochondria

  By Pamela Weintrub in Experience Life.        They’re essential to energy, focus, vitality, and metabolism. And yet most of us have no idea how our mitochondria work. Here’s how to tune up your body’s quadrillions of “energy factories” so you can perform at your peak. We spend billions of dollars every year buying […]

Mitochondrial Dysfunction, Post-Exertional Malaise and ME/CFS

  An interesting read from the Massachusetts CFIDS/ME & FM Association.   Treatment   Living in the “energy envelope” Mitochondrial specialists advise conserving energy to minimize the two types of fatigue. 51 ME/CFS specialists advise acknowledging the finiteness of energy for each patient for each day. Some call this the “energy envelope.” 59, 60, 61Unfortunately, […]

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