Simmaron Research

From The Tahoe Outbreak To COVID-19 Dr. Peterson And Simmaron Take On The Coronavirus – And ME/CFS

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  By Cort Johnson in Simmaron Research.   “Testing is so important to everyone in our community, especially front-line workers and people who are at higher risk of severe disease. Simmaron is excited to serve our neighbors and lead the way to broader testing, so we help keep Nevada safe and learn more about this […]

From The Tahoe Outbreak To COVID-19 Dr. Peterson And Simmaron Take On The Coronavirus – And ME/CFS

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  By Cort Johnson in Simmaron Research.   “Testing is so important to everyone in our community, especially front-line workers and people who are at higher risk of severe disease. Simmaron is excited to serve our neighbors and lead the way to broader testing, so we help keep Nevada safe and learn more about this […]

The Blood Vessel Crunch: A Unifying Hypothesis For ME/CFS

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  By Cort Johnson in Simmaron Research.   This is another hypothesis paper that gives one hope – and makes one wonder if the authors might have a handle on what’s happening with chronic fatigue syndrome (ME/CFS). The paper proposes that a tantalizingly simple problem – an autoimmune attack on just one receptor – out […]

Will COVID-19 Leave An Explosion Of ME/CFS Cases In Its Wake ?

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  By Cort Johnson in Simmaron Health.   The first SARS epidemic in 2003 featuring SARS-CoV now seems like a poor dress rehearsal for today’s SARS CoV-2 outbreak. With just 8,000 cases in total and 774 deaths, (compared to almost 1,000,000 cases and 4,000 plus deaths and rising rapidly) it seems hardly worth including in the same […]

Will COVID-19 Leave An Explosion Of ME/CFS Cases In Its Wake ?

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By Cort Johnson in Simmaron Research.   The first SARS epidemic in 2003 featuring SARS-CoV now seems like a poor dress rehearsal for today’s SARS CoV-2 outbreak. With just 8,000 cases in total and 774 deaths, (compared to almost 1,000,000 cases and 4,000 plus deaths and rising rapidly) it seems hardly worth including in the same sentence. […]

New Pathways: A Step Towards Fine-Tuning Treatments For ME/CFS ?

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    By Cort Johnson in Simmaron Research.   Most chronic fatigue syndrome (ME/CFS) studies focus on females, but for once we have a study contrasting females and males. It makes sense that this group – hailing from Dr. Klimas’s Institute for Neuroimmune Studies, the University of Miami, the Veterans Center in Miami, the University […]

Solid Ground At Last ? Cytokines Make Good In Major ME/CFS Review

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  By Cort Johnson in Simmaron Research.   The immune system in chronic fatigue syndrome (ME/CFS) has been kind of like a mirage in the desert. Given the way the disease starts and its symptom presentation – so close to the “sickness behavior” produced during an infection – it seems that the immune system must […]

ME/CFS Seahorse Energy Production Study Shows Surprises

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    By Cort Johnson in Simmaron Research.   Dr. Maureen Hanson leads one of the three NIH funded ME/CFS research centers, but her ME/CFS research doesn’t stop there.  Using samples from Dr. Daniel Peterson provided by the Simmaron Research Foundation, she’s also been assessing the metabolism of one of the most important cells in […]

The Epstein-Barr Virus – Could It Be Causing Neuroinflammation In ME/CFS ?

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    By Cort Johnson in Simmaron Research.   BV has been a virus of interest since almost day one in chronic fatigue syndrome (ME/CFS). In fact, at one point, EBV was such a hot topic that ME/CFS was called for a time “chronic Epstein-Barr virus” disease. While studies have generally failed to find evidence […]

East African Disease Informs Nath’s Search For The Cause Of ME/CFS

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    By Cort Johnson in Simmaron Research.   Could a disease found in the remote villages of East Africa end up being a model for chronic fatigue syndrome (ME/CFS)? Dr. Avindra Nath – the leader of the NIH Intramural study on ME/CFS –  thinks perhaps so. He’s not daunted by mysterious diseases and nor […]

Could The Brain’s Mast Cells Be Causing Chronic Fatigue Syndrome (ME/CFS) ?

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By Cort Johnson in Simmaron Research.   We propose that stimulation of hypothalamic mast cells by environmental neuroimmune pathogenic and stress triggers activates microglia leading to focal inflammation in the brain and disturbed homeostasis.” Theoharides et. al., 2018 Dr. Theoharis Theoharides is an MD and PhD who has published almost 400 papers. A pioneer in […]

Autoimmune Model Proposes Chronic Fatigue Syndrome (ME/CFS) Begins In The Gut

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    By Cort Johnson in Simmaron Research.   Jonas Blomberg’s paper “Infection Elicited Autoimmunity and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: An Explanatory Model” was published in “Frontiers in Immunology”, an apt journal for a paper featuring an “explanatory model” of chronic fatigue syndrome (ME/CFS). Autoimmunity is definitely a new “frontier”; as Blomberg points out, it’s possibility […]

System Reset ? Study Suggests Pro-Inflammatory / Autoimmune Reset Occurred In Chronic Fatigue Syndrome (ME/CFS)

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  By Cort Johnson in Simmaron Research.   Epigenetics research holds the fascinating possibility of figuring out what shifted at the very beginning of chronic fatigue syndrome (ME/CFS).  For many with ME/CFS a sudden change occurred – some sort of biological reset quickly happened – which never relinquished itself. Finding out what “reset” occurred is […]

Major Research Group Highlights Inflammation Energy Production Connection In ME/CFS

Scientist using a microscope

  By Cort Johnson. The Simmaron Research Foundation is bringing the brain, the immune system and metabolism together in a way that’s never been seen before. “We propose that chronic low-grade inflammation induces and/or maintains persistent fatigue by inducing an imbalance between cellular-energy availability and cellular- and behavioral energy expenditure.” Lacourt et al. 2018 Neurosci. […]

The Autoimmune Virus ? Groundbreaking EBV Finding Could Help Explain ME/CFS

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  By Cort Johnson in Simmaron Research.   Viral Mystery  “I’ve been a co-author in almost 500 papers. This one is more important than all of the rest put together. It is a capstone to a career in medical research,” Harley I sensed some awe in Ron Davis’s voice as he pushed for more understanding of Epstein-Barr […]

NEID Disease ? Study Suggests Neuro, Endocrine And Immune Systems Work Together To Produce ME/CFS

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  By Cort Johnson in Simmaron Research.   Bruun Wyller continues to surprise. When last heard from this erstwhile cognitive behavioral therapy (CBT) proponent asserted that more research into Epstein-Barr virus in chronic fatigue syndrome (ME/CFS) was needed. Now he’s looking at the interaction between the immune and endocrine systems. Wyller begins his new study […]

Could Chronic Fatigue Syndrome (ME/CFS) Be A Chronic Form Of Sepsis ?

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  By Cort Johnson in Simmaron Research.   This is one of a series of blogs highlighting hypotheses mostly written by doctors or other professionals with ME/CFS, or in this case, doctors who have cared for them. The hypothesis examined in this case: Dr. Bell’s idea, produced in his monograph, “Cellular Hypoxia and Neuro-immune Fatigue”, […]

Ian Lipkin & Simmaron To Collaborate In New NIH ME/CFS Research Center

Dr Ian Lipkin

  By Cort Johnson and Courtney Miller in Simmaron Research. (Dr Ian Lipkin pictured) “These important grants will provide a strong foundation for expanding research in ME/CFS, and lead to knowledge about the causes and ways to treat people affected by this mysterious, heartbreaking, and debilitating disease,” Dr. Francis S. Collins, Director of the NIH Simmaron […]

Is Poor Sleep Pummelling the Immune System In ME/CFS And Fibromyalgia ? A Vicious Circle Examined

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    By Cort Johnson in Simmaron Research.   Most people with chronic fatigues syndrome (ME/CFS) and fibromyalgia (FM) know the consequences of poor sleep – the fatigue and pain, the difficulty concentrating, the irritability and more. Sleep is when our body rejuvenates itself; no sleep – no rejuvenation. Given how important sleep is to […]

Major Stanford Study Indicates Chronic Fatigue Syndrome (ME/CFS) Is Inflammatory Disorder

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  By Cort Johnson in Simmaron Research.   There’s been a great deal of controversy and confusion surrounding ME/CFS — even whether it is an actual disease. Our findings show clearly that it’s an inflammatory disease and provide a solid basis for a diagnostic blood test.” Mark Davis There’s nothing like a high-profile study from a […]

The Big Fishing Expedition: Report From The NIH Intramural Study On ME/CFS

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    By Cort Johnson in Simmaron Research.   The NIH’s Intramural Study on ME/CFS now underway is almost certainly the most comprehensive chronic fatigue syndrome (ME/CFS) study ever done. In fact, it may be one of the more multi-faceted studies done in any disease. It’s breadth is astonishing. Besides the blood, urine, fecal matter […]

Even “Minor” Infections Can Cause Chronic Fatigue Syndrome (ME/CFS)

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By Cort Johnson in Simmaron Research.   Giardia hasn’t historically ranked high as a potential cause of chronic fatigue syndrome (ME/CFS). Some anecdotal reports suggest that a Giardia outbreak may have occurred prior to the Incline Village ME/CFS outbreak in the 1980’s. More recently, Corinne Blandino’s severe, decades long case of ME/CFS – which originated with […]

Making Music – And A Difference – For ME/CFS

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  By Cort Johnson in Simmaron Research.   Making Music For ME/CFS For the second time this month, the loved one of an ME/CFS patient has dedicated talent and sacrifice to raise funding for Simmaron Research and awareness of the disease more broadly. Michael Jasper met Terry’s husband, Silvestre, 13 years ago and over time […]

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