The Case For IVIG Treatment In Chronic Fatigue Syndrome (ME/CFS), Fibromyalgia, Small Fiber Neuropathy, And POTS : IVIG#3



By Cort Johnson in Health Rising.


“The bottom line is that we should rethink this whole area and encourage proper clinical trials.” Dr. Nancy Klimas

This article is the last of a three-part series on IVIG which came out of my attending the 2018 Dysautonomia Conference in Nashville, Tennessee.

IVIG is a very expensive but commonly prescribed immune modulating drug used extensively in autoimmunity and immune deficiency. The article examines the evidence base for IVIG in chronic fatigue syndrome (ME/CFS), fibromyalgia and POTS and looks to the future to see what possibilities may emerge.

I queried ME/CFS experts on their use of IVIG in ME/CFS/FM and did a literature search. Four experts answered – Dr. Lapp, Dr. Sivieri, Dr. Klimas and Dr. Levine. Dr. Lapp and Dr. Sivieri sent short replies and Dr. Klimas and Dr. Levine – both obviously very interested in this drug – sent several page-long answers. Dr. Klimas, an immunologist, provided both a historical and present-day overview of the drug’s use in ME/CFS.


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