Analysing Antibody Responses Against EBV-Derived Antigens In ME/CFS



From ME Research UK.

Principal investigators

Dr Nuno Sepúlveda & Prof. Carmen Scheibenbogen.

Background and Aim.

The emergence of so-called ‘long COVID’ has highlighted the potential long-term health consequences of infection with a virus like SARS-CoV-2, leading to symptoms such as fatigue, muscle pain and brain fog that may last for weeks or months.

Of course, this is a familiar scenario to many people with ME/CFS whose illness started shortly after being infected with a virus. Not to mention the similarities in symptoms between ME/CFS and long COVID.

So it is no surprise that significant biomedical research into the causes of ME/CFS over the years has focused on the role of viral infection as a trigger for the illness. In particular, specific viruses such as Epstein-Barr virus (EBV) and human endogenous retroviruses (HERVs) have attracted special attention.


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