D-Ribose For Fibromyalgia & Chronic Fatigue Syndrome


D Ribose


By Adrienne Dellwo in Very Well.


D-ribose is a supplement that’s sometimes recommended for people with fibromyalgia and chronic fatigue syndrome. Also called ribose or Beta-D-ribofuranose, it is a type of sugar that your body produces naturally. It plays several important roles in your body:

  • it helps produce energy in the form of ATP (adenosine triphosphate)
  • it’s a building block of the genetic material RNA (ribonucleic acid)
  • it help increase your muscle energy

As with most supplements, we don’t have enough high-quality research to draw a lot of conclusions about it.

D-Ribose for Fibromyalgia & Chronic Fatigue Syndrome

We have very little research on d-ribose supplementation for either fibromyalgia or chronic fatigue syndrome. Still, some health-care providers recommend it, and some people with these conditions say it is an effective part of their treatment regimen.

One small study concluded that d-ribose supplementation significantly improved symptoms of these conditions, including:

  • increasing energy levels
  • improving sleep quality
  • improving mental clarity
  • lowering pain intensity
  • improving overall well being

However, this work is preliminary and we need more research to confirm the findings.


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