Myalgic Encephalopathy Associated With Cellular Energy Strain

By University of Bergen

Professor Karl Johan Tronstad at the University of Bergen has supervised a study which found biochemical changes in the blood of ME patients. The results support the hypothesis that the disease involves impaired cellular energy metabolism.

ME (Myalgic Encephalopathy), also known as Chronic Fatigue Syndrome (CFS), can be a debilitating disease. It frequently presents after an infection, and key features are long-lasting fatigue and worsening of symptoms after exertion. Symptoms include flu-like malaise, muscle and joint pains, headaches, and cognitive problems.

One hypothesis suggests that ME is caused by an irregularity in the patients’ immune system. This assumption was supported by the observations of oncologists Olav Mella and Øystein Fluge at Haukeland University Hospital, who found that some cancer patients who also suffered from ME, experienced an improvement in ME symptoms when they were given immunosuppressive cancer treatment.

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