PACE Trial’s Findings Fundamentally Challenged By A New Study

Research

 

 

By Simon McGrath in ME/CFS Research Review.

 

In a nutshell: Analysing PACE the way the authors originally promised to do showed that CBT and GET didn’t do much to improve self-reported physical function and fatigue and did not lead to recovery. Even the very limited self-reported gains in this unblinded trial are likely to be illusory because they are not backed up by meaningful gains in objective measures, such as fitness. The self-report gains also appear not to last. We now need biomedical research to pave the way for effective treatments.

Researchers and patients have been pointing out problems with the PACE trial for years. A new paper goes further by reanalysing the raw data to give the results the way the trial authors originally said they would give them, before they opted for softer measures of success. The new paper, published in the journal BMC Psychology, also sets out all the flaws of the PACE trial in one place.

 

To read the rest of this story, click on the link below:

 

Link to PACE Trial story

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