PACE Trial’s ‘Sister’ Study Overlooked

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Sasha Nimmo reports on David Tuller’s blog in #MEAction.

 

In his Virology blog post, David Tuller examines results of ‘sister’ to the PACE trial

In 2003, when the United Kingdom (UK) Medical Research Council announced the PACE trial, they also announced the Fatigue Intervention by Nurses Evaluation (FINE) trial. Why haven’t we heard more about it?  David Tuller examined the study, the results and how the results were shared in “Why has the PACE Study’s “Sister Trial” been “Disappeared” and Forgotten”. Below is a summary of David’s fascinating findings.

Announcing the trial

The FINE trial tested two treatments: pragmatic rehabilitation and supportive listening (alongside a control group). The trial used the Oxford criteria, the same as PACE. The Medical Research Council announced it at the same time as the PACE trial and committed 1.3 million pounds. It included 296 participants.

The theory behind the FINE trial was similar to PACE’s. Physical symptoms were presumed to be the result of “deconditioning” or “dysregulation” caused by sedentary behavior, disrupted sleep cycles and stress. The sedentary behavior was presumed to be due to patients’ “unhelpful” conviction that they suffered from a progressive medical illness.

 

To read the rest of this story, click on the link below:

 

Link to David Tuller’s blog

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