Trial By Error: Null Outcomes Presented As Success In Yet Another CBT Trial from Prof Trudie Chalder

By David Tuller, DrPH i Virology Blog.

Trudie Chalder, a professor of cognitive behavior therapy (CBT) at King’s College London, has recently published yet another high-profile paper: the main results for “efficacy” from a trial of CBT for patients with so-called “persistent physical symptoms” (PPS) in secondary care. As usual with this group of investigators, things haven’t turned out well. But despite null results for the primary outcome, Professor Chalder and her like-minded colleagues have cast the findings in a positive light in their article, published in Psychological Medicine

(Psychological Medicine also published the bogus 2013 “recovery” paper from the PACE team; Professor Chalder was one of the three lead investigators for this classic of likely research misconduct, in which participants could get worse on the primary outcomes and still be deemed. to be “recovered.” When I complained to the editors about it a few years ago, I was advised to replicate the PACE trial; instead, I wrote a letter to the journal that demanded an immediate retraction and garnered more than 100 signatories.)

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