From LDN Research Trust.
What is LDN?
Naltrexone is in a class of drug known as an opiate antagonists. Its normal use is in treating addiction to opiate drugs such as heroin or morphine. The dose used for this purpose is usually between 50 and 300 mg daily.
Low-dose Naltrexone (LDN) has been used in the treatment of autoimmune diseases in the USA since 1985, but is relatively new in the United Kingdom and Europe. Despite the fact that the drug is used at a very low dose, the occurrence of significant introductory or long term side effects cannot be excluded.
This method was devised and subsequently developed by the late Dr Bernard Bihari, M.D., a physician from New York, USA who passed away May 16, 2010. Dr Bihari was qualified in Internal Medicine, Psychiatry and Neurology, and we hope to honor him by continuing his pioneering work.
Suggested Method of Therapy
Your doctor will usually start treatment at an ultra-low dose and increase this gradually over a period of weeks – until you are stable and side effect free.
The starting dose can vary from 0.5 mg to 1.5 mg – and is usually increased over 4 – 8 weeks to 4.5 mg or higher. Some doctors increase this to twice daily, for certain medical conditions.
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